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70 ek282 multi science  (R&D Systems)


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    Structured Review

    R&D Systems 70 ek282 multi science
    70 Ek282 Multi Science, supplied by R&D Systems, used in various techniques. Bioz Stars score: 92/100, based on 9 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/70 ek282 multi science/product/R&D Systems
    Average 92 stars, based on 9 article reviews
    70 ek282 multi science - by Bioz Stars, 2026-05
    92/100 stars

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    92
    R&D Systems 70 ek282 multi science
    70 Ek282 Multi Science, supplied by R&D Systems, used in various techniques. Bioz Stars score: 92/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/70 ek282 multi science/product/R&D Systems
    Average 92 stars, based on 1 article reviews
    70 ek282 multi science - by Bioz Stars, 2026-05
    92/100 stars
      Buy from Supplier

    93
    R&D Systems tnf α 70 ek282 multi science china
    PL improves survival rate, coagulation, and inflammation indicators in CLP mice. A It is a survival analysis for the experimental mice ( n = 12 mice per group; Kaplan–Meier survival analysis). B – I Using ELISA kits in mice plasma, TF, PAI-1, TAT, D-dimer, IL-6, <t>IL-1β,</t> <t>TNF-α,</t> and fibrinogen concentrations were determined ( n = 6/group). Values are shown as mean ± SD. ** P < 0.01 versus sham group; ## P < 0.01 versus CLP group.
    Tnf α 70 Ek282 Multi Science China, supplied by R&D Systems, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/tnf α 70 ek282 multi science china/product/R&D Systems
    Average 93 stars, based on 1 article reviews
    tnf α 70 ek282 multi science china - by Bioz Stars, 2026-05
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    PL improves survival rate, coagulation, and inflammation indicators in CLP mice. A It is a survival analysis for the experimental mice ( n = 12 mice per group; Kaplan–Meier survival analysis). B – I Using ELISA kits in mice plasma, TF, PAI-1, TAT, D-dimer, IL-6, IL-1β, TNF-α, and fibrinogen concentrations were determined ( n = 6/group). Values are shown as mean ± SD. ** P < 0.01 versus sham group; ## P < 0.01 versus CLP group.

    Journal: Inflammation

    Article Title: Piperlongumin Improves Survival in the Mouse Model of Sepsis: Effect on Coagulation Factors and Lung Inflammation

    doi: 10.1007/s10753-022-01709-x

    Figure Lengend Snippet: PL improves survival rate, coagulation, and inflammation indicators in CLP mice. A It is a survival analysis for the experimental mice ( n = 12 mice per group; Kaplan–Meier survival analysis). B – I Using ELISA kits in mice plasma, TF, PAI-1, TAT, D-dimer, IL-6, IL-1β, TNF-α, and fibrinogen concentrations were determined ( n = 6/group). Values are shown as mean ± SD. ** P < 0.01 versus sham group; ## P < 0.01 versus CLP group.

    Article Snippet: The reagent kits are as follows: IL-6 (70-EK206, Multi Science, China), IL-1β (70-EK201B, Multi Science, China), TNF-α (70-EK282, Multi Science, China), TF (DY3178-05, R&D systems, USA), PAI-1 (DY3828-05 R&D systems, USA), D-dimer (CSB-E13584m, Cusabio, China), fibrinogen (CSB-E08202m, Cusabio, China), and TAT (CSB-E08433m, Cusabio, China).

    Techniques: Coagulation, Enzyme-linked Immunosorbent Assay

    PL alleviates inflammation and fibrin deposition in the lungs of CLP mice. A HE-stained images of lungs in each group were observed under an optical microscope (scale bar: 10 µm). B Lung injury score was evaluated according to the degree and scope of lung injury, including the degree of interstitial edema, septal wall thickness, and inflammatory cell infiltration. C Representative images of immunohistochemical staining of fibrin were obtained in the lungs from three groups of mice (400 ×). D The western blot results showed IL-1β, TNF-α, and IL-6 protein levels in lung tissues, and the relative expression levels of IL-1β, TNF-α, and IL-6 normalized to tubulin. Values are shown as mean ± SD. ** P < 0.01 versus sham group; ## P < 0.01 versus CLP group.

    Journal: Inflammation

    Article Title: Piperlongumin Improves Survival in the Mouse Model of Sepsis: Effect on Coagulation Factors and Lung Inflammation

    doi: 10.1007/s10753-022-01709-x

    Figure Lengend Snippet: PL alleviates inflammation and fibrin deposition in the lungs of CLP mice. A HE-stained images of lungs in each group were observed under an optical microscope (scale bar: 10 µm). B Lung injury score was evaluated according to the degree and scope of lung injury, including the degree of interstitial edema, septal wall thickness, and inflammatory cell infiltration. C Representative images of immunohistochemical staining of fibrin were obtained in the lungs from three groups of mice (400 ×). D The western blot results showed IL-1β, TNF-α, and IL-6 protein levels in lung tissues, and the relative expression levels of IL-1β, TNF-α, and IL-6 normalized to tubulin. Values are shown as mean ± SD. ** P < 0.01 versus sham group; ## P < 0.01 versus CLP group.

    Article Snippet: The reagent kits are as follows: IL-6 (70-EK206, Multi Science, China), IL-1β (70-EK201B, Multi Science, China), TNF-α (70-EK282, Multi Science, China), TF (DY3178-05, R&D systems, USA), PAI-1 (DY3828-05 R&D systems, USA), D-dimer (CSB-E13584m, Cusabio, China), fibrinogen (CSB-E08202m, Cusabio, China), and TAT (CSB-E08433m, Cusabio, China).

    Techniques: Staining, Microscopy, Immunohistochemical staining, Western Blot, Expressing

    Screening the appropriate concentration of PL. A The CCK-8 assay detected the viability of RAW264.7 cells at different concentrations of PL. B Half maximum inhibitory concentration of PL that inhibits RAW264.7 cells. C , D PL (1.25 or 2.5 µM) was added 2 h before LPS (1 µg/mL, 6 h) treatment, and the qRT-PCR was used to assess the relative mRNA levels of IL-1β and TNF-α. Every experiment was repeated three times. Values are indicated as mean ± SD. ** P < 0.01 versus control group; ## P < 0.01 versus LPS group; NS, not significant versus control group.

    Journal: Inflammation

    Article Title: Piperlongumin Improves Survival in the Mouse Model of Sepsis: Effect on Coagulation Factors and Lung Inflammation

    doi: 10.1007/s10753-022-01709-x

    Figure Lengend Snippet: Screening the appropriate concentration of PL. A The CCK-8 assay detected the viability of RAW264.7 cells at different concentrations of PL. B Half maximum inhibitory concentration of PL that inhibits RAW264.7 cells. C , D PL (1.25 or 2.5 µM) was added 2 h before LPS (1 µg/mL, 6 h) treatment, and the qRT-PCR was used to assess the relative mRNA levels of IL-1β and TNF-α. Every experiment was repeated three times. Values are indicated as mean ± SD. ** P < 0.01 versus control group; ## P < 0.01 versus LPS group; NS, not significant versus control group.

    Article Snippet: The reagent kits are as follows: IL-6 (70-EK206, Multi Science, China), IL-1β (70-EK201B, Multi Science, China), TNF-α (70-EK282, Multi Science, China), TF (DY3178-05, R&D systems, USA), PAI-1 (DY3828-05 R&D systems, USA), D-dimer (CSB-E13584m, Cusabio, China), fibrinogen (CSB-E08202m, Cusabio, China), and TAT (CSB-E08433m, Cusabio, China).

    Techniques: Concentration Assay, CCK-8 Assay, Quantitative RT-PCR, Control

    PL suppresses the inflammation in RAW264.7 cells induced by LPS. A – C PL (2.5 µM) was added 2 h before LPS (1 µg/mL, 6 h) treatment, and each group’s mRNA expression levels of TNF-α, IL-6, and IL-1β were analyzed by qRT-PCR. D – F ELISA analysis of TNF-α, IL-6, and IL-1β concentrations in RAW264.7 supernatant. G The western blot results show phosphorylation levels of NF-κB p65 and IκBα in LPS-stimulated RAW264.7 cells. Every indicator was detected three times. Values are indicated as mean ± SD. ** P < 0.01 versus control group; # P < 0.05, ## P < 0.01 versus LPS group.

    Journal: Inflammation

    Article Title: Piperlongumin Improves Survival in the Mouse Model of Sepsis: Effect on Coagulation Factors and Lung Inflammation

    doi: 10.1007/s10753-022-01709-x

    Figure Lengend Snippet: PL suppresses the inflammation in RAW264.7 cells induced by LPS. A – C PL (2.5 µM) was added 2 h before LPS (1 µg/mL, 6 h) treatment, and each group’s mRNA expression levels of TNF-α, IL-6, and IL-1β were analyzed by qRT-PCR. D – F ELISA analysis of TNF-α, IL-6, and IL-1β concentrations in RAW264.7 supernatant. G The western blot results show phosphorylation levels of NF-κB p65 and IκBα in LPS-stimulated RAW264.7 cells. Every indicator was detected three times. Values are indicated as mean ± SD. ** P < 0.01 versus control group; # P < 0.05, ## P < 0.01 versus LPS group.

    Article Snippet: The reagent kits are as follows: IL-6 (70-EK206, Multi Science, China), IL-1β (70-EK201B, Multi Science, China), TNF-α (70-EK282, Multi Science, China), TF (DY3178-05, R&D systems, USA), PAI-1 (DY3828-05 R&D systems, USA), D-dimer (CSB-E13584m, Cusabio, China), fibrinogen (CSB-E08202m, Cusabio, China), and TAT (CSB-E08433m, Cusabio, China).

    Techniques: Expressing, Quantitative RT-PCR, Enzyme-linked Immunosorbent Assay, Western Blot, Control